Oligosaccharides from Marine Algae- V. Antitumor Activity of Oligosaccharides Derived from Porphyra yezoensis Porphyran.

Isolation of porphyran-degrading marine microorganisms from the surface of red alga, Porphyra yezoensis.

Marine microorganisms degrading porphyran (POR) were found on the surface of thalli of Porphyra yezoensis. Fifteen crude microorganism groups softened and liquefied the surface of agar-rich plate medium. Among these, 11 microorganism groups degraded porphyran that consisted of sulfated polysaccharide in Porphyra yezoensis. Following isolation, 7 POR-degradable microorganisms were isolated from ...

Algae-Derived Marine Oligosaccharides and Their Biological Applications

The biological relevance of algae-derived marine oligosaccharides has potential significance in numerous applications of industrial biotechnology. Marine oligosaccharides are produced in algae naturally and/or by hydrolysis of derived polysaccharides. The potential of marine oligosaccharides is still unexplored, and these molecules, including their derivatives, are a versatile source of chemica...

Preparation and antihypertensive activity of peptides from Porphyra yezoensis

This research was to develop a antihypertensive peptide, an efficient angiotensin converting enzyme (ACE) inhibitor (ACEI), from Porphyra yezoensis. Seven commercial enzymes were screened and then enzymatic hydrolysis conditions were optimised. The results showed that alcalase was the most effective for hydrolysis and its optimum conditions for achieving the highest antihypertensive activity of...

Stability of Oligosaccharides Derived from Lactulose

Effect of dietary porphyran from the red alga, Porphyra yezoensis, on glucose metabolism in diabetic KK-Ay mice.

Porphyran (POR) from the red alga Porphyra yezoensis is a water soluble dietary fiber. In this study, we investigated the effect of dietary POR on glucose metabolism in KK-Ay mice (a model for type 2 diabetes). Mice were divided into 4 groups and fed a diet containing 5% cellulose (control), POR, POR Arg or POR K. After 3 wk of feeding, plasma insulin levels and the calculated homeostasis model...